VINORELBINE TARTRATE (Generic for NAVELBINE)

Vinorelbine Tartrate 10mg/1mL, Solution for injection

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: Do not eat or drink grapefruit or grapefruit juice without talking to your doctor or healthcare professional while taking Vinorelbine. Grapefruit may increase the risk of side effects from Vinorelbine. Tell your health care provider immediately if you notice new or worsening constipation, stomach or abdominal pain, tingling in fingers and/or toes, or inability to pick-up items with your fingers.

· Notes for Professionals: Instruct patients that consuming grapefruit or grapefruit juice may result in earlier onset and/or increased severity of vinorelbine-related adverse reactions, including constipation and peripheral neuropathy. Vinorelbine is a CYP3A4 substrate and grapefruit juice is a strong CYP3A4 inhibitor.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>