Twyneo Food, Alcohol, Supplements and Drug Interactions

TWYNEO

QTY 30 • 0.1 %-3 % • Cream (g) • Near 77381

TRETINOIN; BENZOYL PEROXIDE (TRET i noe in; BEN zoe ill per OX ide) treats acne. It works by decreasing inflammation and promoting skin cell turnover to prevent clogged pores. It also kills and prevents the growth of bacteria that cause acne. It is a combination of a retinoid and an antiseptic.

TWYNEO Lifestyle Interactions

Tretinoin 0.1%, Benzoyl Peroxide 3%, Topical cream

Grapefruit juice

· Severity: Major

· Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.

· Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during tretinoin treatment due to the risk of increased tretinoin exposure and adverse reactions. Tretinoin is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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Prescription prices may vary from pharmacy to pharmacy and are subject to change. The pricing estimates given are based on the most recent information available and may change based on when you actually fill your prescription at the pharmacy.

DISCOUNT ONLY - NOT INSURANCE. Discounts are available exclusively through participating pharmacies. The range of the discounts will vary depending on the type of prescription and the pharmacy chosen. This program does not make payments directly to pharmacies. Members are required to pay for all prescription purchases. Cannot be used in conjunction with insurance. You may contact customer care anytime with questions or concerns, to cancel your registration, or to obtain further information. This program is administered by Medical Security Card Company, LLC, Tucson, AZ.

*Average and up to savings percentages are based on all discounted prescriptions that were run through the WellRx program in 2022. Discount percentages represent savings provided off of pharmacies’ retail prices for consumers who do not have a discount program and pay cash.

The day supply is based upon the average dispensing patterns for the specific drug and strength. The Program, as well as the prices and the list of covered drugs, can be modified at any time without notice.

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