ORGOVYX

Relugolix 120mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: Do not take Relugolix with grapefruit or grapefruit juice. Side effects of Relugolix may get worse. If you accidentally take Relugolix with grapefruit or grapefruit juice, immediately tell your doctor about any unusual effects including chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your heartbeat (such as a fast or irregular heartbeat).

· Notes for Professionals: Instruct patients to avoid grapefruit or grapefruit juice with relugolix due to increased plasma concentrations of relugolix, which may increase the incidence and severity of adverse reactions. Relugolix is a P-glycoprotein (P-gp) substrate; grapefruit juice is a P-gp inhibitor.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>