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NALOXEGOL (nal OX e GAHL) treats constipation caused by opioids. It works by blocking the effect of opioids in your intestine, which helps the muscles in your intestine move stool. This helps produce a bowel movement. It belongs to a group of medications called opioid blockers.
Naloxegol 25mg, Oral tablet
Grapefruit juice
· Severity: Severe
· Notes for Consumers: Do not take Grapefruit juice with Naloxegol. Consuming Grapefruit Juice or grapefruit-containing foods may increase the risk of serious side effects from Naloxegol.
· Notes for Professionals: Patients should avoid grapefruit and grapefruit juice during naloxegol treatment. Concomitant use of naloxegol with grapefruit juice is contraindicated. Naloxegol is metabolized primarily by CYP3A. Strong CYP3A4 inhibitors, such as grapefruit juice, can significantly increase exposure to naloxegol which may precipitate opioid withdrawal symptoms such as hyperhidrosis, chills, diarrhea, abdominal pain, anxiety, irritability, and yawning.
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Number of Uses:
movantik
25 MG | Tablet | 30 tablets
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