MARAVIROC (Generic for SELZENTRY)

Maraviroc 300mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: It is best to avoid Grapefruit or Grapefruit Juice while taking Maraviroc. Side effects from Maraviroc may get worse. Notify your health care provider if you experience chest pain, symptoms of infection, rash, symptoms of potential liver problems, or other new or unusual side effects.

· Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during maraviroc therapy. Coadministration of maraviroc, a CYP3A substrate, with grapefruit juice, a strong CYP3A4 inhibitor, may result in increased maraviroc concentrations and increased side effects. Reduce the dose of maraviroc when it is used with other strong CYP3A inhibitors; coadministration of maraviroc with strong CYP3A inhibitors is contraindicated in patients with CrCl less than 30 mL/minute.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>