LDO PLUS

Lidocaine Hydrochloride 4%, Spiraea ulmaria flower extract, Oak Bark, Zinc Acetate, Topical gel

Cannabis

· Severity: Major

· Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis.

· Notes for Professionals: Advise patients to avoid cannabis use during lidocaine treatment due to decreased exposure of lidocaine which may alter its efficacy. Cannabis use induces CYP1A2 and lidocaine is a CYP1A2 substrate. The induction potential of cannabis is greatest with chronic inhalation. Other routes of administration or sporadic use may have less of an effect.

Lidocaine Hydrochloride 4%, Spiraea ulmaria flower extract, Oak Bark, Zinc Acetate, Topical gel

Enteral Feedings

· Severity: Mild

· Notes for Consumers: If you need to use Enteral feedings (examples: Ensure, Jevity and others) as your sole nutritional dietary intake for long periods of time, you may be at risk for Zinc deficiency, as the feeding may impair the absorption of zinc. This interaction is not a concern if you simply use these products as supplements to a normal diet; true zinc deficiency is relatively rare. If you take Enteral Feedings as your only diet for long periods of time, you may need to discuss the use of additional mineral supplements with your prescriber. If you do take a Zinc supplement, it is best to take it at least 1 hour before or 1 hour after you have taken any feeding, meal, or beverage.

· Notes for Professionals: Absorption of zinc from enteral feedings may be impaired, despite the presence of zinc as a component of the enteral feeding formula; patients on chronic enteral feeding therapy may require additional zinc supplementation to ensure adequate nutritional intake.

Lidocaine Hydrochloride 4%, Spiraea ulmaria flower extract, Oak Bark, Zinc Acetate, Topical gel

Food

· Severity: Moderate

· Notes for Consumers: Taking oral Zinc Salts (dietary supplements or medicines like Galzin, Zinc Sulfate, etc.) at the same time as food or beverages, other than water, can reduce the amount of zinc absorbed. Breads, vegetables, fruits, eggs, and beverages like milk or coffee are all known to decrease zinc supplement absorption. If you do take a Zinc supplement, it is best to take it at least 1 hour before or 1 hour after you have taken any feeding, meal, or beverage.

· Notes for Professionals: Breads, vegetables, fruits, eggs, and beverages appear to interfere with the oral absorption of Zinc. For optimal absorption, oral zinc salts should be separated from food and beverages, other than water, by at least 1 hour.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>