Lapatinib Food, Alcohol, Supplements and Drug Interactions

LAPATINIB (Generic for TYKERB)

QTY 150 • 250 MG • Tablet • Near 77381

LAPATINIB/Tykerb (la PA ti nib) treats breast cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

LAPATINIB (Generic for TYKERB) Lifestyle Interactions

Lapatinib 250mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: Do not take Lapatinib with Grapefruit or Grapefruit juice. Side effects of Lapatinib may get worse. If you accidentally take Lapatinib with grapefruit or grapefruit juice, immediately tell your doctor about any unusual effects.

· Notes for Professionals: Avoid administration of lapatinib with grapefruit juice due to increased plasma concentrations of lapatinib. Lapatinib is a CYP3A4 substrate and grapefruit juice is a strong CYP3A4 inhibitor. Concomitant use with another strong CYP3A4 inhibitor increased lapatinib exposure by 3.6-fold and increased the half-life of lapatinib by 1.7-fold.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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Prescription prices may vary from pharmacy to pharmacy and are subject to change. The pricing estimates given are based on the most recent information available and may change based on when you actually fill your prescription at the pharmacy.

DISCOUNT ONLY - NOT INSURANCE. Discounts are available exclusively through participating pharmacies. The range of the discounts will vary depending on the type of prescription and the pharmacy chosen. This program does not make payments directly to pharmacies. Members are required to pay for all prescription purchases. Cannot be used in conjunction with insurance. You may contact customer care anytime with questions or concerns, to cancel your registration, or to obtain further information. This program is administered by Medical Security Card Company, LLC, Tucson, AZ.

*Average and up to savings percentages are based on all discounted prescriptions that were run through the WellRx program in 2022. Discount percentages represent savings provided off of pharmacies’ retail prices for consumers who do not have a discount program and pay cash.

The day supply is based upon the average dispensing patterns for the specific drug and strength. The Program, as well as the prices and the list of covered drugs, can be modified at any time without notice.

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