JUXTAPID

Lomitapide 5mg, Oral capsule

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication increases the risk of liver injury. Contact your care team right away if you experience right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, or unusual weakness or fatigue.

· Notes for Professionals: Alcohol may increase levels of hepatic fat and induce or exacerbate liver injury. Patients taking lomitapide should not consume more than one alcohol-containing drink per day.

Lomitapide 5mg, Oral capsule

Grapefruit juice

· Severity: Severe

· Notes for Consumers: Do not take drink grapefruit juice while taking lomitapide. Grapefruit juice may increase the amount of lomitapide in your body and increase the risk for serious side effects from lomitapide.

· Notes for Professionals: Grapefruit juice must be omitted from the diet during lomitapide therapy. Grapefruit juice inhibits the enterocyte CYP3A4 isoenzyme and may decrease lomitapide metabolism.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>