HUMALOG MIX 75-25

Insulin Lispro Protamine (NPL) 75U/1mL, Insulin Lispro 25U/1mL, Suspension for injection

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication increases the risk for a dangerous decrease in your blood sugar (hypoglycemia). Contact your care team if you experience tremors or shaking, anxiety, sweating, cold or clammy skin, confusion, dizziness, or a rapid heartbeat.

· Notes for Professionals: Patients should be advised to avoid or limit alcohol ingestion when treated with insulin. Alcohol ingestion increases hypoglycemic risk. In some patients, hypoglycemia can be prolonged. Educate regarding the importance of glucose monitoring, as well as the signs, symptoms, and self-management of delayed hypoglycemia after drinking alcohol, especially when using insulin. Moderate alcohol intake does not have major detrimental effects on long-term blood glucose management in people with diabetes.

Insulin Lispro Protamine (NPL) 75U/1mL, Insulin Lispro 25U/1mL, Suspension for injection

Tobacco

· Severity: Major

· Notes for Consumers: Do not smoke or use tobacco products while taking this medication. When used together, your medication may not work as well for you.

· Notes for Professionals: Advise patients to avoid smoking tobacco while taking insulin. Tobacco smoking is known to aggravate insulin resistance. The cessation of nicotine therapy or tobacco smoking may result in a decrease in blood glucose. Blood glucose concentrations should be monitored more closely whenever a change in either nicotine intake or smoking status occurs; dosage adjustments in antidiabetic agents may be needed.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>