GOCOVRI

Amantadine 137mg, Oral capsule, extended release

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause serious side effects, such as central nervous system (CNS) depression and dangerously low blood pressure, and can increase the risk of falling. Call emergency services right away if you experience symptoms of CNS depression: slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake. Contact your care team right away if you experience symptoms of dangerously low blood pressure: dizziness, feeling faint or lightheaded, blurry vision.

· Notes for Professionals: Advise patients to avoid alcohol while taking amantadine. Concomitant use with alcohol may increase the potential for CNS effects such as dizziness, confusion, lightheadedness, and orthostatic hypotension. In addition, if the patient is using amantadine extended-release (ER), alcohol use may result in amantadine dose-dumping and toxicity.

Amantadine 137mg, Oral capsule, extended release

Caffeine-containing Foods/Beverages

· Severity: Major

· Notes for Consumers: Limit caffeine use while taking amantadine. This includes limiting caffeine intake in foods (examples coffees, colas, teas, and chocolate), in medicines, and in herbal supplements.

· Notes for Professionals: Amantadine used concomitantly with psychostimulants, such as caffeine, can result in increased stimulant effects, such as nervousness, irritability, or insomnia, and can lead to seizures or cardiac arrhythmias. Close monitoring of the patient is recommended.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>