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FLUOROURACIL/Efudex (flure oh YOOR a sil) treats rough, scaly spots on the skin caused by sun exposure. It may also be used to treat skin cancer. It works by slowing down the growth of irregular skin cells.
Fluorouracil 5%, Topical cream
Cannabis
· Severity: Major
· Notes for Consumers: Discuss cannabis use with your care team. The effects of cannabis may be altered if used with your medication. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.
· Notes for Professionals: Advise patients to avoid cannabis use during fluorouracil treatment. Concomitant use may alter the exposure of some cannabinoids and increase the risk for adverse reactions. The cannabinoid delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are CYP2C9 substrates and fluorouracil is a moderate CYP2C9 inhibitor.
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Number of Uses:
fluorouracil
5 % | Cream (g) | 40 grams
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