DOPTELET

Avatrombopag 20mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: Do not eat or drink grapefruit or grapefruit juice while on Avatrombopag therapy without approval from your prescriber. Grapefruit may increase Avatrombopag side effects. Contact your health care provider if you experience new or worsening side effects such as headache, fatigue, joint pain, unusual bruising, red spots on the skin, or bleeding from the gums or nose.

· Notes for Professionals: Avoid consumption of grapefruit during avatrombopag therapy. Avatrombopag is a CYP2C9 and CYP3A4 substrate, dual moderate or strong inhibitors such as grapefruit juice increase avatrombopag exposure, increasing the risk of avatrombopag toxicity.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>