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CLINDAMYCIN; TRETINOIN (KLIN da MYE sin; TRET i noe in) treats acne. It works by killing or preventing the growth of bacteria that cause acne. It also decreases inflammation and promotes skin cell turnover to prevent pores from clogging. It is a combination of an antibiotic and a retinoid.
Clindamycin Phosphate 1.2%, Tretinoin 0.025%, Topical gel
Grapefruit juice
· Severity: Moderate
· Notes for Consumers: Although an interaction is possible, Clindamycin and Grapefruit Juice may be used together with caution. Side effects may get worse if you take these drugs together. Discuss any new or worsening side effects, such as diarrhea, abdominal pain, and vomiting, with your health care provider.
· Notes for Professionals: Monitor for an increase in clindamycin-related adverse reactions with coadministration of grapefruit juice as concurrent use may increase clindamycin exposure. Clindamycin is a CYP3A4 substrate; grapefruit juice is a strong inhibitor of CYP3A4.
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Number of Uses:
clindamycin phos-tretinoin
1.2-0.025% | Gel | 60 grams
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