BROMOCRIPTINE MESYLATE (Generic for PARLODEL)

Bromocriptine Mesylate 2.5mg, Oral tablet

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause serious side effects, such as central nervous system (CNS) depression and dangerously low blood pressure, and can increase the risk of falling. Call emergency services right away if you experience symptoms of CNS depression: slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake. Contact your care team right away if you experience symptoms of dangerously low blood pressure: dizziness, feeling faint or lightheaded, blurry vision.

· Notes for Professionals: Alcohol may potentiate some of the side effects of bromocriptine, including hypotension and somnolence. Patients should be advised to avoid alcohol and not to drive or engage in activities where impaired alertness may put themselves or others at risk of serious injury (e.g., operating machines) until the effects of bromocriptine are known.

Bromocriptine Mesylate 2.5mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: Do not take grapefruit juice with bromocriptine without approval from your prescriber. Side effects may get worse if you take grapefruit juice together with bromocriptine. Contact your healthcare provider if you experience new or worsening side effects including confusion, hallucination, loss of contact with reality, falling asleep during normal activities like driving, nausea, tiredness, dizziness, vomiting, and headache.

· Notes for Professionals: Patients should avoid the use of grapefruit juice when bromocriptine is used for treatment of diabetes, ensuring adequate washout before initiating bromocriptine. Use this combination with caution in patients receiving bromocriptine for other indications. Concurrent use may significantly increase bromocriptine concentrations. Bromocriptine is extensively metabolized in the liver via CYP3A4; grapefruit juice is a strong inhibitor of CYP3A4.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>