BICALUTAMIDE (Generic for CASODEX)

Bicalutamide 50mg, Oral tablet

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: Substances which are potent inhibitors of the elimination of Bicalutamide may increase Bicalutamide concentrations, and therefore, increase potential for side effects. Side effects or increased toxicity associated with Bicalutamide may be observed. Notify your health care provider if you notice changes in your infection status or other unusual effects.

· Notes for Professionals: Substances that are potent inhibitors of CYP3A4 activity decrease the metabolism of bicalutamide and increase bicalutamide concentrations. This increase may be clinically relevant as adverse reactions to bicalutamide are related to dose and exposure; therefore caution should be used when administering CYP3A4 inhibitors, such as grapefruit juice. with bicalutamide.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>