Copyright 2025
Medical Security Card Company, LLC
All Rights Reserved
ATENOLOL/Tenormin (a TEN oh lole) treats high blood pressure. It also prevents chest pain (angina) or further damage after a heart attack. It works by lowering your blood pressure and heart rate, making it easier for your heart to pump blood to the rest of your body. It belongs to a group of medications called beta blockers.
Atenolol 25mg, Oral tablet
Food
· Severity: Moderate
· Notes for Consumers: Atenolol may be taken without regard to most food or meals. There is one small study that suggests taking atenolol with orange juice directly might moderately lower atenolol's effectiveness. More data are needed to confirm these results. Why this interaction might occur is not known at this time. Until more data are available, it may be advisable to not significantly alter your orange juice intake while taking atenolol.
· Notes for Professionals: Coadministration of oral atenolol with most foods/meals does not appear to be a problem despite a 20% reduction in bioavailability. Administration directly with orange juice might have a moderately significant effect by decreasing bioavailability and mean Cmax by roughly 40%. Data are from a small single dose study in healthy volunteers. It is not known if this potential interaction results in clinically significant effects on heart rate or blood pressure reduction in populations of interest.