PIMECROLIMUS (Generic for ELIDEL)

Pimecrolimus 1%, Topical cream

Alcohol

· Severity: Moderate

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause flushing.

· Notes for Professionals: A flushing syndrome (alcohol intolerance) has been reported in patients treated with topical pimecrolimus upon ingestion of alcohol. The flushing occurred in the face or at the sites of medication application, usually within 5 to 15 minutes of alcohol ingestion, and lasted for an average duration of 1 hour. Patients describe redness and warm sensations, which sometimes result in discomfort. The reaction does not appear to occur in all patients; roughly 3% to 7% report a notable effect. The possible mechanism of the effect is the inhibition of acetaldehyde dehydrogenase, leading to increased acetaldehyde dehydrogenase concentrations in the skin.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>