ORKAMBI

Take this medication by mouth with fat-containing foods such as eggs, avocados, nuts, butter, peanut butter, or cheese pizza. Breast milk, infant formula, whole-milk dairy products (such as whole milk, cheese, and yogurt) may also be used. Take it as directed on the prescription label. Keep taking it unless your care team tells you to stop.
Do not take this medication with grapefruit juice.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 6 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
This medication may cause cataracts, especially in children. You should have regular eye exams while taking this medication. Tell your care team if you have changes in your eyesight.
Estrogen and progestin hormones may not work as well while you are taking this medication. Your care team can help you find the contraceptive option that works for you.

If you miss a dose, take it as soon as you can. If your next dose is to be taken in less than 6 hours, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses.

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.