MOMETASONE FUROATE (Generic for ELOCON)

Mometasone Furoate 0.1%, Topical ointment

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: These agents may be taken together with close supervision from your prescriber. Taking these drugs together could result in serious side effects such as mood changes; nausea, vomiting; dizziness; feeling faint or lightheaded, falls; unusually weak or tired; high blood pressure; skin changes; weight loss or gain. Report any of these effects immediately should they occur.

· Notes for Professionals: Consumption of grapefruit or grapefruit juice while taking mometasone may increase systemic exposure to mometasone, increasing the risk of corticosteroid-related adverse events. Avoid consistent consumption of grapefruit and its juice while on mometasone therapy; those who do consume grapefruit regularly should be monitored closely for hypercorticism and adrenal suppression. Mometasone is a CYP3A4 substrate and grapefruit is a strong CYP3A4 inhibitor.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>