Farydak Food, Alcohol, Supplements and Drug Interactions

FARYDAK

QTY 6 • 10 MG • Capsule • Near 77381

PANOBINOSTAT (pan oh bin oh stat) is a chemotherapy drug that targets a specific protein within cancer cells and stops the cancer cells from growing. It is used to treat multiple myeloma.

FARYDAK Lifestyle Interactions

Panobinostat 10mg, Oral capsule

Grapefruit juice

· Severity: Major

· Notes for Consumers: Do not eat grapefruit or drink grapefruit juice with panobinostat. This fruit can increase the levels of panobinostat in your body and you may experience more side effects.

· Notes for Professionals: Avoid taking star fruit, pomegranate or pomegranate juice, and grapefruit or grapefruit juice with panobinostat. These fruits are strong CYP3A4 inhibitors and panobinostat is a CYP3A4 substrate. The panobinostat Cmax and AUC (0-48hr) values were increased by 62% and 73%, respectively, in patients with advanced cancer who received a single 20 mg-dose of panobinostat after taking 14 days of a strong CYP3A4 inhibitor.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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